League Leaders - Offense
| Passing Yards | Complete List | |
Trevor Lawrence
|
1. Trevor Lawrence, LAC | 1471 |
| 2. Marquise Richards, ARI | 1168 | |
| 3. Daniel Rayford, LAR | 32 | |
| 4. Lawrence Wendling, DAL | 19 | |
| 5. Bryant Quinn, TEN | 12 | |
| Rushing Yards | Complete List | |
Quinterrius Higgins
|
1. Quinterrius Higgins, IND | 425 |
| 2. Caddarreus Dunn, NE | 325 | |
| 3. Gareef Peete, NO | 233 | |
| 4. Marquiste Vines, ATL | 131 | |
| 5. Bryan Watters, CIN | 121 | |
| Receiving Yards | Complete List | |
Caddarreus Dunn
|
1. Caddarreus Dunn, NE | 246 |
| 2. LeVeon Frazier, NYJ | 207 | |
| 3. Quinterrius Higgins, IND | 132 | |
| 4. Marquiste Vines, ATL | 89 | |
| 5. Gifford Richie, BUF | 83 | |
League Leaders - Defense
| Tackles | Complete List | |
Stanley Pyne
|
1. Stanley Pyne, HOU | 41 |
| 2. Allen Bodiford, ATL | 36 | |
| 3. Lamarcus Bennett, CAR | 34 | |
| 4. Walker Newell, GB | 34 | |
| 5. Shundrez Cudjo, KC | 33 | |
| Sacks | Complete List | |
Lamarcus Bennett
|
1. Lamarcus Bennett, CAR | 4 |
| 2. Cameron Pope, BUF | 4 | |
| 3. Chase Rollins, CLE | 3 | |
| 4. Berry Paul, TEN | 2 | |
| 5. Marquiste Massey, SEA | 2 | |
| Interceptions | Complete List | |
Iron Mike Tyson
|
1. Iron Mike Tyson, ARI | 2 |
| 2. Lamarcus Bennett, CAR | 2 | |
| 3. DeVan Reeves, BUF | 1 | |
| 4. Tyrus Baldwin, JAX | 1 | |
| 5. Stanley Pyne, HOU | 1 | |