League Leaders - Offense
| Passing Yards | Complete List | |
Kirk Cousins
|
1. Kirk Cousins, MIN | 766 |
| 2. Lamar Jackson, BAL | 651 | |
| 3. Andrew Luck, IND | 584 | |
| 4. Andy Dalton, TB | 582 | |
| 5. Dak Prescott, DAL | 572 | |
| Rushing Yards | Complete List | |
Derrius Guice
|
1. Derrius Guice, WAS | 317 |
| 2. Tarik Cohen, CHI | 290 | |
| 3. Todd Gurley II, LAR | 290 | |
| 4. Duke Johnson Jr, HOU | 259 | |
| 5. David Johnson, ARI | 237 | |
| Receiving Yards | Complete List | |
Jakeem Grant
|
1. Jakeem Grant, DEN | 328 |
| 2. Scott Miller, MIN | 324 | |
| 3. Parris Campbell, IND | 284 | |
| 4. Corey Davis, TEN | 249 | |
| 5. Jarvis Landry, CLE | 243 | |
League Leaders - Defense
| Tackles | Complete List | |
Ricardo Allen
|
1. Ricardo Allen, ATL | 13 |
| 2. Lonnie Ballentine, NYG | 11 | |
| 3. Devin Bush, PIT | 10 | |
| 4. Jaquiski Tartt, SF | 10 | |
| 5. Khalil Mack, CHI | 10 | |
| Sacks | Complete List | |
Khalil Mack
|
1. Khalil Mack, CHI | 9 |
| 2. Montez Sweat, WAS | 6 | |
| 3. Geno Atkins, DEN | 6 | |
| 4. DeMarcus Lawrence, DAL | 5 | |
| 5. Brian Burns, CAR | 5 | |
| Interceptions | Complete List | |
Briean Boddy-Calhoun
|
1. Briean Boddy-Calhoun, HOU | 5 |
| 2. Patrick Peterson, CAR | 4 | |
| 3. Byron Jones, DAL | 3 | |
| 4. Sean Murphy-Bunting, TB | 2 | |
| 5. Kenny Moore II, PIT | 2 | |