League Leaders - Offense
| Passing Yards | Complete List | |
Kenan Powell
|
1. Kenan Powell, SEA | 850 |
| 2. Tommy Tipton, LAR | 803 | |
| 3. Leonard Gabriel, DET | 500 | |
| 4. John Edison, JAX | 405 | |
| 5. Wyatt Clapp, MIN | 12 | |
| Rushing Yards | Complete List | |
Nick Carter
|
1. Nick Carter, CHI | 289 |
| 2. Clayton Weeks, HOU | 197 | |
| 3. Antwan Trent, DAL | 44 | |
| 4. Anthony Clements, PIT | 19 | |
| 5. Tommy Tipton, LAR | 13 | |
| Receiving Yards | Complete List | |
Sean Jackson
|
1. Sean Jackson, SEA | 285 |
| 2. Steven Love, LAC | 268 | |
| 3. Terrell Irwin, PIT | 244 | |
| 4. Jeffrey Randolph, CLE | 235 | |
| 5. Brian Blair, LAR | 147 | |
League Leaders - Defense
| Tackles | Complete List | |
Brendan Thompson
|
1. Brendan Thompson, KC | 10 |
| 2. Terrelle Upshaw, CHI | 10 | |
| 3. Chris Bramble, IND | 9 | |
| 4. Jalen Strong, JAX | 8 | |
| 5. Joshua Lashley, NYJ | 8 | |
| Sacks | Complete List | |
|
Brendan Thompson
|
1. Brendan Thompson, KC | 4 |
| 2. Casey Capers, PIT | 4 | |
| 3. Kendall Ricks, NYJ | 3 | |
| 4. Jalen Strong, JAX | 2 | |
| 5. Joshua Lashley, NYJ | 2 | |
| Interceptions | Complete List | |
Keenan Levine
|
1. Keenan Levine, HOU | 3 |
| 2. Joshua Lashley, NYJ | 2 | |
| 3. Terrelle Upshaw, CHI | 2 | |
| 4. Mike Zimmerman, IND | 2 | |
| 5. Damarius Murdock, JAX | 1 | |